Pathophysiology roles and translational opportunities of miRNAs in ovarian cancer

Ben Davidson; Reuven Reich

doi:10.1016/b978-0-12-822287-4.00004-9

Pathophysiology roles and translational opportunities of miRNAs in ovarian cancer

Ben Davidson, Reuven Reich

School of Pharmacy

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Ovarian cancer, consists predominantly of ovarian carcinoma, of which high-grade serous carcinoma is the most common and most clinically aggressive histotype. Recent studies, focusing mainly on the latter histotype, have highlighted the critical role of miRNA in regulating processes that are central to the biology and clinical behavior of this cancer. In addition to intracellular miRNAs, knowledge has been gained regarding extracellular miRNAs, including those packed in exosomes, and their central role in cross-talk between tumor and host cells. This chapter reviews selected studies focusing on the role of miRNAs in ovarian cancer that have been published in recent years.

Original language	English
Title of host publication	MicroRNA in Human Malignancies
Publisher	Elsevier
Pages	317-322
Number of pages	6
ISBN (Electronic)	9780128222874
ISBN (Print)	9780128232743
DOIs	https://doi.org/10.1016/b978-0-12-822287-4.00004-9
State	Published - 1 Jan 2022

Bibliographical note

Publisher Copyright:
© 2022 Elsevier Inc. All rights reserved.

Keywords

Exosomes
Extracellular miRNA
High-grade serous carcinoma
Ovarian cancer
Tumor progression

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/b978-0-12-822287-4.00004-9

Cite this

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Pathophysiology roles and translational opportunities of miRNAs in ovarian cancer

Abstract

Bibliographical note

Keywords

UN SDGs

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