PDZBase: A protein-protein interaction database for PDZ-domains

Thijs Beuming, Lucy Skrabanek, Masha Y. Niv, Piali Mukherjee, Harel Weinstein*

*Corresponding author for this work

Research output: Contribution to journalComment/debate

165 Scopus citations

Abstract

Summary: PDZBase is a database that aims to contain all known PDZ-domain-mediated protein-protein interactions. Currently, PDZ-Base contains approximately 300 such interactions, which have been manually extracted from >200 articles. The database can be queried through both sequence motif and keyword-based searches, and the sequences of interacting proteins can be visually inspected through alignments (for the comparison of several interactions), or as residue-based diagrams including schematic secondary structure information (for individual complexes).

Original languageAmerican English
Pages (from-to)827-828
Number of pages2
JournalBioinformatics
Volume21
Issue number6
DOIs
StatePublished - 15 Mar 2005
Externally publishedYes

Bibliographical note

Funding Information:
We thank Dr Nathalie Basdevant for curating part of the interactions. The work is supported by NIH grants K05 DA00060, P01 DA124080 and P01 DA12923.

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