Abstract
Summary: PDZBase is a database that aims to contain all known PDZ-domain-mediated protein-protein interactions. Currently, PDZ-Base contains approximately 300 such interactions, which have been manually extracted from >200 articles. The database can be queried through both sequence motif and keyword-based searches, and the sequences of interacting proteins can be visually inspected through alignments (for the comparison of several interactions), or as residue-based diagrams including schematic secondary structure information (for individual complexes).
Original language | English |
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Pages (from-to) | 827-828 |
Number of pages | 2 |
Journal | Bioinformatics |
Volume | 21 |
Issue number | 6 |
DOIs |
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State | Published - 15 Mar 2005 |
Externally published | Yes |
Bibliographical note
Funding Information:We thank Dr Nathalie Basdevant for curating part of the interactions. The work is supported by NIH grants K05 DA00060, P01 DA124080 and P01 DA12923.