PeCoP: Automatic determination of persistently conserved positions in protein families

Iddo Friedberg; Hanah Margalit

doi:10.1093/bioinformatics/18.9.1276

PeCoP: Automatic determination of persistently conserved positions in protein families

Iddo Friedberg^*, Hanah Margalit

^*Corresponding author for this work

Institute for Medical Research Israel-Canada (IMRIC)

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Summary: PeCoP is a WWW-based service which accepts a protein sequence, and reports positions that are conserved in close and distant sequence family members. The collation of family members is performed using iterative PSI-BLAST runs. Examining positional conservation in close and distant family members enables a better selection of positions that may play a role in determining the protein's structure and function.

Original language	English
Pages (from-to)	1276-1277
Number of pages	2
Journal	Bioinformatics
Volume	18
Issue number	9
DOIs	https://doi.org/10.1093/bioinformatics/18.9.1276
State	Published - Sep 2002

Bibliographical note

Funding Information:
The authors wish to thank Bioinformatics.Org (director: J.W.Bizzaro) for hosting and help in setting up the PeCoP site. This study was supported by a strategic grant from the Israel Ministry of Science and by a grant from the Israel Science Foundation administered by the Israel Academy of Science and Humanities.

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10.1093/bioinformatics/18.9.1276

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PeCoP: Automatic determination of persistently conserved positions in protein families

Abstract

Bibliographical note

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