PeCoP: Automatic determination of persistently conserved positions in protein families

Iddo Friedberg*, Hanah Margalit

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Summary: PeCoP is a WWW-based service which accepts a protein sequence, and reports positions that are conserved in close and distant sequence family members. The collation of family members is performed using iterative PSI-BLAST runs. Examining positional conservation in close and distant family members enables a better selection of positions that may play a role in determining the protein's structure and function.

Original languageAmerican English
Pages (from-to)1276-1277
Number of pages2
JournalBioinformatics
Volume18
Issue number9
DOIs
StatePublished - Sep 2002

Bibliographical note

Funding Information:
The authors wish to thank Bioinformatics.Org (director: J.W.Bizzaro) for hosting and help in setting up the PeCoP site. This study was supported by a strategic grant from the Israel Ministry of Science and by a grant from the Israel Science Foundation administered by the Israel Academy of Science and Humanities.

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