TY - JOUR
T1 - PEG-Biscyanoacrylate Crosslinker for Octyl Cyanoacrylate Bioadhesive
AU - Basu, Arijit
AU - Veprinsky-Zuzulia, Ilana
AU - Levinman, Mira
AU - Barkan, Yoav
AU - Golenser, Jacob
AU - Domb, Abraham J.
N1 - Publisher Copyright:
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
PY - 2016/2/1
Y1 - 2016/2/1
N2 - PEG400 (polyethylene glycol, MW 400) biscyanoacrylate is synthesized and copolymerized with 2-octyl cyanoacrylate for potential use as bioadhesive. PEG400 biscyanoacrylate is synthesized from the esterification of anthracenyl cyanoacrylic acid where the anthracene unit serves as vinyl-protecting group. Copolymerization increases the plasticity, mechanical strength, and resilience of the resulted polymer as determined by dynamic mechanical analysis. Peeling test confirms its superior bioadhesive properties. Surface morphology is characterized by SEM imaging. The formulations are cytocompatible and safe. This cyanoacrylate composition may provide improved bioadhesive cyanoacrylates.
AB - PEG400 (polyethylene glycol, MW 400) biscyanoacrylate is synthesized and copolymerized with 2-octyl cyanoacrylate for potential use as bioadhesive. PEG400 biscyanoacrylate is synthesized from the esterification of anthracenyl cyanoacrylic acid where the anthracene unit serves as vinyl-protecting group. Copolymerization increases the plasticity, mechanical strength, and resilience of the resulted polymer as determined by dynamic mechanical analysis. Peeling test confirms its superior bioadhesive properties. Surface morphology is characterized by SEM imaging. The formulations are cytocompatible and safe. This cyanoacrylate composition may provide improved bioadhesive cyanoacrylates.
KW - 2-octyl cyanoacrylate
KW - bioadhesives
KW - PEG biscyanoacrylate
KW - plasticity
KW - viscoelasticity
UR - http://www.scopus.com/inward/record.url?scp=84956900144&partnerID=8YFLogxK
U2 - 10.1002/marc.201500567
DO - 10.1002/marc.201500567
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C2 - 26572088
AN - SCOPUS:84956900144
SN - 1022-1336
VL - 37
SP - 251
EP - 256
JO - Macromolecular Rapid Communications
JF - Macromolecular Rapid Communications
IS - 3
ER -