TY - JOUR
T1 - Periodontal disease might be associated even with impaired fasting glucose
AU - Zadik, Y.
AU - Bechor, R.
AU - Galor, S.
AU - Levin, L.
PY - 2010/5/22
Y1 - 2010/5/22
N2 - Objective To determine whether there is an association between fasting plasma glucose level and periodontal condition in a non-diabetic male population.Methods Data of periodic medical examinations of 815 non-diabetic male adults (mean age 38.1 ± 7.0 years) were analysed. Blood samples were drawn from each subject following a 14-hour fast. The distance between the cement-enamel-junction to alveolar bone crest was measured at inter-proximal sites on two standardised posterior bitewing radiographs.Results Higher prevalence of alveolar bone loss was found among individuals with a fasting glucose level of ≥ 100 mg/dL than among individuals with <100 mg/dL (p = 0.032) and among individuals with BMI ≥25 than among individuals with BMI ≤25 (p = 0.025). Associations were found between bone loss prevalence and serum triglyceride levels of ≥ 200mg/dL, total cholesterol level of ≥ 200mg/dL and LDL-cholesterol level of ≥ 130mg/dL (p = 0.010, p ≤0.001, p = 0.009, respectively).Conclusions In the studied non-diabetic adult population, periodontal disease was associated with impaired glucose level. Periodontal disease could serve as a predictor for future diabetes mellitus, or play a possible role in the glucose imbalance and diabetes mellitus development.
AB - Objective To determine whether there is an association between fasting plasma glucose level and periodontal condition in a non-diabetic male population.Methods Data of periodic medical examinations of 815 non-diabetic male adults (mean age 38.1 ± 7.0 years) were analysed. Blood samples were drawn from each subject following a 14-hour fast. The distance between the cement-enamel-junction to alveolar bone crest was measured at inter-proximal sites on two standardised posterior bitewing radiographs.Results Higher prevalence of alveolar bone loss was found among individuals with a fasting glucose level of ≥ 100 mg/dL than among individuals with <100 mg/dL (p = 0.032) and among individuals with BMI ≥25 than among individuals with BMI ≤25 (p = 0.025). Associations were found between bone loss prevalence and serum triglyceride levels of ≥ 200mg/dL, total cholesterol level of ≥ 200mg/dL and LDL-cholesterol level of ≥ 130mg/dL (p = 0.010, p ≤0.001, p = 0.009, respectively).Conclusions In the studied non-diabetic adult population, periodontal disease was associated with impaired glucose level. Periodontal disease could serve as a predictor for future diabetes mellitus, or play a possible role in the glucose imbalance and diabetes mellitus development.
UR - http://www.scopus.com/inward/record.url?scp=77952878042&partnerID=8YFLogxK
U2 - 10.1038/sj.bdj.2010.291
DO - 10.1038/sj.bdj.2010.291
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C2 - 20339371
AN - SCOPUS:77952878042
SN - 0007-0610
VL - 208
JO - British Dental Journal
JF - British Dental Journal
IS - 10
M1 - E20
ER -