TY - JOUR
T1 - Phosphatidylserine in the outer leaflet of red blood cells from β‐thalassemia patients may explain the chronic hypercoagulable state and thrombotic episodes
AU - Yashar, Vered Borenstain‐Ben
AU - Barenholz, Yechezkel
AU - Hy‐Am, Esther
AU - Rachmilewitz, Eliezer A.
AU - Eldor, Amiram
PY - 1993/9
Y1 - 1993/9
N2 - Investigation of red blood cells from β‐thalassemia patients by means of prothrombinase assay reveals phosphatidylserine in the outer leaflet of the plasma membrane. This might explain their elevated susceptibility to phagocytosis by macrophages and the chronic hypercoagulable state, frequent thrombotic events, and life‐long platelet activation that are found in thalassemic patients. © 1993 Wiley‐Liss, Inc.
AB - Investigation of red blood cells from β‐thalassemia patients by means of prothrombinase assay reveals phosphatidylserine in the outer leaflet of the plasma membrane. This might explain their elevated susceptibility to phagocytosis by macrophages and the chronic hypercoagulable state, frequent thrombotic events, and life‐long platelet activation that are found in thalassemic patients. © 1993 Wiley‐Liss, Inc.
KW - membrane asymmetry
KW - prothrombinase assay
KW - red blood cells
KW - β‐thalassemia
UR - http://www.scopus.com/inward/record.url?scp=0027161045&partnerID=8YFLogxK
U2 - 10.1002/ajh.2830440114
DO - 10.1002/ajh.2830440114
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C2 - 8342566
AN - SCOPUS:0027161045
SN - 0361-8609
VL - 44
SP - 63
EP - 65
JO - American Journal of Hematology
JF - American Journal of Hematology
IS - 1
ER -