Physiology and pathology of eosinophils: Recent developments: Summary of the Focus Workshop Organized by DGAKI

Harald Renz*, Claus Bachert, Claudia Berek, Eckard Hamelmann, Francesca Levi-Schaffer, Ulrike Raap, Hans Uwe Simon, Sabine Ploetz, Christian Taube, Peter Valent, David Voehringer, Thomas Werfel, Nan Zhang, Johannes Ring

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations

Abstract

Over the last century, eosinophils have been regarded ambiguously either as ‘friends’ or ‘foes’. Recent developments have greatly enhanced our understanding of the role and function of eosinophils in health and disease. Pathogenic eosinophilic inflammation can lead to severe diseases in various organs, such as the gastrointestinal tract, airways, heart and skin. In a 2-day focus workshop of the German Society for Allergology and Clinical Immunology (DGAKI), the state of the art was discussed and practical recommendations for diagnosis and treatment of eosinophilic diseases, with a particular focus on new biologics, such as anti-interleukin 5 and anti-interleukin 5R, were derived.

Original languageAmerican English
Article numbere13032
JournalScandinavian Journal of Immunology
Volume93
Issue number6
DOIs
StatePublished - Jun 2021

Bibliographical note

Publisher Copyright:
© 2021 The Authors. Scandinavian Journal of Immunology published by John Wiley & Sons Ltd on behalf of The Scandinavian Foundation for Immunology.

Keywords

  • DNAzyme against GATA3; eosinophil
  • anti-interleukin 5
  • eosinophil diseases
  • hypereosinophilic syndrome

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