Plaque Inhibition by Sustained Release of Chlorhexidine from Removable Appliances

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Abstract

We studied the effectiveness of a sustained-release delivery system for chlorhexidine in plaque prevention. A clinical trial in a group of eight students wearing orthodontic appliances coated by ethyl cellulose polymer containing the drug demonstrated that plaque accumulation was decreased for a period of four days. All oral procedures had been withdrawn during the clinical study. No side-effects of chlorhexidine, such as tooth staining and unpleasant taste, were observed.

Original languageEnglish
Pages (from-to)1319-1321
Number of pages3
JournalJournal of Dental Research
Volume64
Issue number11
DOIs
StatePublished - Nov 1985

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