Plasma volume regulation during heat stress: Albumin synthesis vs capillary permeability. A comparison between desert and non-desert species

Michal Horowitz*, Johnathan H. Adler

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

1. 1. Plasma albumin synthesis was measured in rats and sand rats (Psammomys obesus) during heat acclimation (34°C) and following thermal dehydration (37°C) using 3H l-leucine as a tracer. 2. 2. In rats, heat acclimation resulted in 48% reduction in albumin synthesis. In sand rats synthesis increased by 160%. Both species achieved a new stabilization of the albumin synthetic system on the 5th day of acclimation. 3. 3. Following thermal dehydration albumin synthesis increased in rats and decreased in sand rats. Acclimation did not alter this response. 4. 4. In our dehydrating system plasma volume was maintained via maintenance of adequate albumin mass. In rats, albumin synthesis apparently contributes to this process. In sand rat, vascular permeability rather than albumin synthesis plays this role.

Original languageEnglish
Pages (from-to)105-110
Number of pages6
JournalComparative Biochemistry and Physiology -Part A : Molecular and Integrative Physiology
Volume75
Issue number1
DOIs
StatePublished - 1983

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