Plasmid-mediated qnrB2 and carbapenemase gene blaKPC-2 carried on the same plasmid in carbapenem-resistant ciprofloxacin-susceptible Enterobacter cloacae isolates

Inna Chmelnitsky; Shiri Navon-Venezia; Jacob Strahilevitz; Yehuda Carmeli

doi:10.1128/AAC.01341-07

Plasmid-mediated qnrB2 and carbapenemase gene bla_KPC-2 carried on the same plasmid in carbapenem-resistant ciprofloxacin-susceptible Enterobacter cloacae isolates

Inna Chmelnitsky
, Shiri Navon-Venezia
, Jacob Strahilevitz
, Yehuda Carmeli^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

39 Scopus citations

Abstract

Fourteen out of 16 carbapenem-resistant quinolone-susceptible Enterobacter cloacae isolates were found to carry qnrB2 and bla_KPC-2 genes encoded on the same plasmid. One isolate also carried the aac(6′)-Ib-cr gene. Coexistence of quinolone resistance determinants and bla_KPC-2 on the same plasmid in quinolone-susceptible E. cloacae isolates may have important clinical implications.

Original language	English
Pages (from-to)	2962-2965
Number of pages	4
Journal	Antimicrobial Agents and Chemotherapy
Volume	52
Issue number	8
DOIs	https://doi.org/10.1128/AAC.01341-07
State	Published - Aug 2008
Externally published	Yes

Access to Document

10.1128/AAC.01341-07

Cite this

@article{2e1fca5273894ce6b75dd66834bb38d1,

title = "Plasmid-mediated qnrB2 and carbapenemase gene blaKPC-2 carried on the same plasmid in carbapenem-resistant ciprofloxacin-susceptible Enterobacter cloacae isolates",

abstract = "Fourteen out of 16 carbapenem-resistant quinolone-susceptible Enterobacter cloacae isolates were found to carry qnrB2 and blaKPC-2 genes encoded on the same plasmid. One isolate also carried the aac(6′)-Ib-cr gene. Coexistence of quinolone resistance determinants and blaKPC-2 on the same plasmid in quinolone-susceptible E. cloacae isolates may have important clinical implications.",

author = "Inna Chmelnitsky and Shiri Navon-Venezia and Jacob Strahilevitz and Yehuda Carmeli",

year = "2008",

month = aug,

doi = "10.1128/AAC.01341-07",

language = "אנגלית",

volume = "52",

pages = "2962--2965",

journal = "Antimicrobial Agents and Chemotherapy",

issn = "0066-4804",

publisher = "American Society for Microbiology",

number = "8",

}

Plasmid-mediated qnrB2 and carbapenemase gene bla_KPC-2 carried on the same plasmid in carbapenem-resistant ciprofloxacin-susceptible Enterobacter cloacae isolates. / Chmelnitsky, Inna; Navon-Venezia, Shiri; Strahilevitz, Jacob et al.
In: Antimicrobial Agents and Chemotherapy, Vol. 52, No. 8, 08.2008, p. 2962-2965.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Plasmid-mediated qnrB2 and carbapenemase gene blaKPC-2 carried on the same plasmid in carbapenem-resistant ciprofloxacin-susceptible Enterobacter cloacae isolates

AU - Chmelnitsky, Inna

AU - Navon-Venezia, Shiri

AU - Strahilevitz, Jacob

AU - Carmeli, Yehuda

PY - 2008/8

Y1 - 2008/8

N2 - Fourteen out of 16 carbapenem-resistant quinolone-susceptible Enterobacter cloacae isolates were found to carry qnrB2 and blaKPC-2 genes encoded on the same plasmid. One isolate also carried the aac(6′)-Ib-cr gene. Coexistence of quinolone resistance determinants and blaKPC-2 on the same plasmid in quinolone-susceptible E. cloacae isolates may have important clinical implications.

AB - Fourteen out of 16 carbapenem-resistant quinolone-susceptible Enterobacter cloacae isolates were found to carry qnrB2 and blaKPC-2 genes encoded on the same plasmid. One isolate also carried the aac(6′)-Ib-cr gene. Coexistence of quinolone resistance determinants and blaKPC-2 on the same plasmid in quinolone-susceptible E. cloacae isolates may have important clinical implications.

UR - https://www.scopus.com/pages/publications/48749098086

U2 - 10.1128/AAC.01341-07

DO - 10.1128/AAC.01341-07

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

C2 - 18519713

AN - SCOPUS:48749098086

SN - 0066-4804

VL - 52

SP - 2962

EP - 2965

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

IS - 8

ER -

Plasmid-mediated qnrB2 and carbapenemase gene bla_KPC-2 carried on the same plasmid in carbapenem-resistant ciprofloxacin-susceptible Enterobacter cloacae isolates

Abstract

Access to Document

Other files and links

Fingerprint

Cite this