Plasmodium berghei: Specific stimulation of rat lymphocytes by soluble antigens released in vitro from infected erythrocytes

H. Weissberger; J. Golenser; D. T. Spira

doi:10.1016/0014-4894(80)90015-6

Plasmodium berghei: Specific stimulation of rat lymphocytes by soluble antigens released in vitro from infected erythrocytes

H. Weissberger^*, J. Golenser, D. T. Spira

^*Corresponding author for this work

Institute for Medical Research Israel-Canada (IMRIC)

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Soluble components released in vitro from rat erythrocytes parasitized with Plasmodium berghei have been shown to stimulate nonadherent spleen lymphocytes from rats convalescent from homologous infection. The active product is released from the infected erythrocytes either spontaneously during incubation, or as the result of artificial rupture of infected erythrocytes by freezing and thawing or sonication. This antigen produced precipitation lines with antiplasmodial antibodies from sera of convalescent and hyperimmune rats and from immunized rabbits.

Original language	English
Pages (from-to)	136-143
Number of pages	8
Journal	Experimental Parasitology
Volume	50
Issue number	1
DOIs	https://doi.org/10.1016/0014-4894(80)90015-6
State	Published - 1980

Keywords

Antigens
Immunity
Lymphoblast transformation
Plasmodium berghei
Protozoa
Rat
Suppressor cells
cell mediated
parasitic
soluble

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10.1016/0014-4894(80)90015-6

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abstract = "Soluble components released in vitro from rat erythrocytes parasitized with Plasmodium berghei have been shown to stimulate nonadherent spleen lymphocytes from rats convalescent from homologous infection. The active product is released from the infected erythrocytes either spontaneously during incubation, or as the result of artificial rupture of infected erythrocytes by freezing and thawing or sonication. This antigen produced precipitation lines with antiplasmodial antibodies from sera of convalescent and hyperimmune rats and from immunized rabbits.",

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KW - Protozoa

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Plasmodium berghei: Specific stimulation of rat lymphocytes by soluble antigens released in vitro from infected erythrocytes

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