Plasticity in auditory cortical circuitry

Ehud Ahissar*, Merav Ahissar

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

46 Scopus citations


Recent studies have focused on the mechanisms and conditions yielding the short- and long-term plasticity exhibited by neuronal responses in the primary auditory cortex of adults. These investigations have examined factors operating at the cellular and intercellular levels, the effects of global behavioral states and the role of the cholinergic system, which could mediate between the global and local levels. A behaviorally gated unsupervised Hebbian-covariance rule can explain most of the bottom-up driven changes that were observed following sensory manipulation. However, additional supervised learning mechanisms are probably required to generate behavioral improvement. This suggestion has not yet been tested directly.

Original languageAmerican English
Pages (from-to)580-587
Number of pages8
JournalCurrent Opinion in Neurobiology
Issue number4
StatePublished - Aug 1994


  • ACh-acetylcholine
  • EEG-electroencephalogram


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