Polioencephalomyelopathy in a mixed breed dog resembling Leigh's disease

Orit Chai*, Joshua Milgram, Merav H. Shamir, Ori Brenner

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


A 14-month-old mixed-breed dog was presented with acute onset of exercise intolerance that quickly progressed to quadriparesis. Gross and microscopic autopsy findings indicated a type of degenerative polioencephalomyelopathy resembling subacute necrotizing encephalomyelopathy in dogs or Leigh's disease in humans. This syndrome has previously been reported only in purebred dogs.

Original languageAmerican English
Pages (from-to)59-62
Number of pages4
JournalCanadian Veterinary Journal
Issue number1
StatePublished - 1 Jan 2015


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