Abstract
Several p‐vinylbenzyl malonates were synthesized and condensed with urea to form the corresponding 5‐p‐vinylbenzyl barbiturates, which were polymerized. The gross behavioral changes observed on intraperitoneal (i.p.) administration of the polybarbiturates to mice were compared with those caused by the monomers. The polymers were less toxic but had weaker sedative effects than their respective monomers, and they did not exhibit any prolongation of activity.
Original language | English |
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Pages (from-to) | 835-840 |
Number of pages | 6 |
Journal | Israel Journal of Chemistry |
Volume | 11 |
Issue number | 6 |
DOIs | |
State | Published - 1973 |