Potential induced pH change: Towards electrochemical coating of medical implants by organic nanoparticles

Ido Levy, Shlomo Magdassi, Daniel Mandler*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

The electrochemical deposition of organic nanoparticles on conducting surface, such as a coronary stents, in the absence of a polymeric matrix is demonstrated. A novel approach, whereby pH-responsive organic nanoparticles coagulate on a conducting surface as a result of applying positive potential, has been studied. Specifically, latex nanoparticles stabilized by sodium oleate in aqueous solutions were deposited by applying a positive potential that oxidized the water and caused the decrease of pH on various conducting surfaces. It was found that the applied potential, its duration and the concentration of the dispersed nanoparticles govern the deposition characteristics of the coating. This generic approach allows coating objects with complex geometries with thickness ranging from nanometers to microns and therefore can be utilized for coating medical and other devices as well as for controlling drug release.

Original languageEnglish
Pages (from-to)8590-8594
Number of pages5
JournalElectrochimica Acta
Volume55
Issue number28
DOIs
StatePublished - 1 Dec 2010

Bibliographical note

Funding Information:
This work was supported by the Applied Science Funds of the Hebrew University of Jerusalem. The Harvey M. Krueger Family Center for Nanoscience and Nanotechnology of the Hebrew University is acknowledged.

Keywords

  • Electrochemistry
  • Latex
  • Medical devices
  • Nanoparticles
  • pH

Fingerprint

Dive into the research topics of 'Potential induced pH change: Towards electrochemical coating of medical implants by organic nanoparticles'. Together they form a unique fingerprint.

Cite this