Preventing pathological regression of blood vessels

Eli Keshet*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

17 Scopus citations

Abstract

Oxygen administration to premature infants suppresses retinal VEGF expression and results in the catastrophic vessel loss associated with retinopathy of prematurity. A study investigating the development of the retinal vasculature in mice (see related article on pages 50-57) demonstrates that specific activation of VEGF receptor-1 by placental growth factor-1 protects against oxygen-induced vessel loss without stimulating vascular proliferation and neovascularization.

Original languageEnglish
Pages (from-to)27-29
Number of pages3
JournalJournal of Clinical Investigation
Volume112
Issue number1
DOIs
StatePublished - Jul 2003

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