Abstract
Oxygen administration to premature infants suppresses retinal VEGF expression and results in the catastrophic vessel loss associated with retinopathy of prematurity. A study investigating the development of the retinal vasculature in mice (see related article on pages 50-57) demonstrates that specific activation of VEGF receptor-1 by placental growth factor-1 protects against oxygen-induced vessel loss without stimulating vascular proliferation and neovascularization.
Original language | English |
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Pages (from-to) | 27-29 |
Number of pages | 3 |
Journal | Journal of Clinical Investigation |
Volume | 112 |
Issue number | 1 |
DOIs | |
State | Published - Jul 2003 |