Primary calcification in remodeling haversian systems following tibial fracture in rats

J. Lowe, I. Bab, H. Stein, J. Sella

Research output: Contribution to journalArticlepeer-review

27 Scopus citations

Abstract

Electron micrographs of fracture callus obtained ten days after injury show typical primary matrix vesicle mineralization. In remodeling haversian canals distant from the fracture sites, matrix vesicles and calcifying nodules were observed. The occurrence of these elements was also found to control unfractured tibiae with intramedullary nails but not normal bone. These observations suggest that during haversian remodeling, mineralization after osseous or marrow tissue damage is associated with matrix vesicles.

Original languageEnglish
Pages (from-to)291-297
Number of pages7
JournalClinical Orthopaedics and Related Research
VolumeNo. 176
StatePublished - 1983
Externally publishedYes

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