Privileged crosstalk between TRPV1 channels and mitochondrial calcium shuttling machinery controls nociception

Keyphrases

• Transient Receptor Potential Vanilloid 1 (TRPV1) 100%
• Mitochondrial Calcium 100%
• TRP Channels 100%
• Nociception 100%
• Sodium 57%
• Mitochondria 28%
• Desensitization 28%
• Mitochondrial Ca2+ 28%
• Cytosolic Calcium 28%
• Calcium-dependent 28%
• Capsaicin 28%
• Dorsal Root Ganglion Neurons 14%
• Intracellular Inclusions 14%
• Knockdown 14%
• HEK293 Cells 14%
• Activating Receptors 14%
• Induced Cell Death 14%
• Electrophysiological Recordings 14%
• Inward Current 14%
• Mitochondrial Ca2+ Uptake 14%
• Sodium Imaging 14%
• Sodium Flux 14%
• Mitochondrial Ca2+ Uniporter 14%
• Nociceptive Neurons 14%
• Receptor Potential 14%
• Sodium Entry 14%
• Ca2+ Entry 14%
• Induced Current 14%
• Neuronal Firing 14%
• Heat-activated 14%
• Nociceptor 14%
• MCU Control 14%
• Calcium Influx 14%
• Fluorescent Calcium Imaging 14%
• Calcium Transporter 14%
• Calcium Chelator 14%
• Cytosolic Calcium Flux 14%
• Noxious Heat 14%
• Decrease Rate 14%
• Small Interfering RNA (siRNA) 14%
• Sodium Influx 14%
• BAPTA 14%
• Excitability 14%

Neuroscience

• Nociception 100%
• Vanilloid Receptor 1 100%
• TRPV1 100%
• Mitochondrion 28%
• Calcium Transport 28%
• Capsaicin 28%
• Sodium Transport 28%
• Excitability 14%
• Dorsal Root Ganglion 14%
• Cell Death 14%
• Nociceptor 14%
• Chelating Agent 14%
• Small Interfering RNA 14%
• Receptor Potential 14%
• Receptor 14%

Biochemistry, Genetics and Molecular Biology

• Nociception 100%
• TRPV1 100%
• Mitochondrion 20%
• Calcium Transport 20%
• Sodium Transport 20%
• Small Interfering RNA 10%
• Excitability 10%
• Uniporter 10%
• Downregulation 10%
• Cell Death 10%
• Electrophysiological Procedures 10%
• Receptor Potential 10%
• Pain Receptor 10%