TY - GEN
T1 - Probing how initial retinal configuration controls photochemical dynamics in retinal proteins
AU - Wand, A.
AU - Rozin, R.
AU - Eliash, T.
AU - Friedman, N.
AU - Jung, K. H.
AU - Sheves, M.
AU - Ruhman, S.
PY - 2013
Y1 - 2013
N2 - The effects of the initial retinal configuration and the active isomerization coordinate on the photochemistry of retinal proteins (RPs) are assessed by comparing photochemical dynamics of two stable retinal ground state configurations (all-trans,15-anti vs. 13-cis,15-syn), within two RPs: Bacteriorhodopsin (BR) and Anabaena Sensory Rhodopsin (ASR). Hyperspectral pump-probe spectroscopy shows that photochemistry starting from 13-cis retinal in both proteins is 3-10 times faster than when started in the all-trans state, suggesting that the hastening is ubiquitous to microbial RPs, regardless of their different biological functions and origin. This may also relate to the known disparity of photochemical rates between microbial RPs and visual pigments. Importance and possible underlying mechanisms are discussed as well.
AB - The effects of the initial retinal configuration and the active isomerization coordinate on the photochemistry of retinal proteins (RPs) are assessed by comparing photochemical dynamics of two stable retinal ground state configurations (all-trans,15-anti vs. 13-cis,15-syn), within two RPs: Bacteriorhodopsin (BR) and Anabaena Sensory Rhodopsin (ASR). Hyperspectral pump-probe spectroscopy shows that photochemistry starting from 13-cis retinal in both proteins is 3-10 times faster than when started in the all-trans state, suggesting that the hastening is ubiquitous to microbial RPs, regardless of their different biological functions and origin. This may also relate to the known disparity of photochemical rates between microbial RPs and visual pigments. Importance and possible underlying mechanisms are discussed as well.
UR - http://www.scopus.com/inward/record.url?scp=84875683693&partnerID=8YFLogxK
U2 - 10.1051/epjconf/20134107018
DO - 10.1051/epjconf/20134107018
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AN - SCOPUS:84875683693
SN - 9782759809561
T3 - EPJ Web of Conferences
BT - 18th International Conference on Ultrafast Phenomena, UP 2012
T2 - 18th International Conference on Ultrafast Phenomena, UP 2012
Y2 - 8 July 2012 through 13 July 2012
ER -