Production of a radioactive 18F ion beam for nuclear reaction studies

A. D. Roberts*, R. J. Nickles, M. Paul, K. E. Rehm, C. L. Jiang, D. J. Blumenthal, J. Gehring, D. Henderson, J. Nolen, R. C. Pardo, J. P. Schiffer, R. E. Segel

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

A two-stage method for generating a radioactive 18F ion beam has been developed. 18F is produced with a medical cyclotron by 11 MeV proton activation of [18O]water, then chemically processed off-line for use in a tandem accelerator ion source. Azeotropic distillation reduces the 18O component by 105, with a resulting 18O to 18F beam ratio of about 103. The average 18F- beam intensity per synthesis is 1 ppA over 120 min from a cesium vapor, sputter negative ion source (SNICS), with a peak intensity of 4.5 ppA.

Original languageEnglish
Pages (from-to)523-528
Number of pages6
JournalNuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms
Volume103
Issue number4
DOIs
StatePublished - 1 Dec 1995

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