Programmed dissociation of dimer and trimer origami structures by aptamer-ligand complexes

Na Wu, Itamar Willner*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

33 Scopus citations

Abstract

Dimer- and trimer-origami frames are bridged by duplexes that include caged, sequence-specific, anti-ATP and/or anti-cocaine aptamer sequences. The programmed dissociation of the origami dimers or trimers in the presence of ATP and/or cocaine ligands is demonstrated. The processes are followed by AFM imaging and by electrophoretic experiments.

Original languageEnglish
Pages (from-to)1416-1422
Number of pages7
JournalNanoscale
Volume9
Issue number4
DOIs
StatePublished - 28 Jan 2017

Bibliographical note

Publisher Copyright:
© 2017 The Royal Society of Chemistry.

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