Properties of afferent nerve impulses originating from a neuroma

Patrick D. Wall*, Michael Gutnick

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

329 Scopus citations

Abstract

Damaged nerves attempt to regenerate. The nerve membrane changes its properties, becomes spontaneously active and may be the source of pain. These impulse generators have unusual properties. They become silent after high frequency activity. This silence may partially explain the effect of counterstimulation as a pain therapy.

Original languageEnglish
Pages (from-to)740-743
Number of pages4
JournalNature
Volume248
Issue number5451
DOIs
StatePublished - 1974

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