Properties of the oncornavirus particles isolated from P3HR-1 and Raji human lymphoblastoid cell lines

M. Kotler, H. Balabanova, Z. Ben-Moyal, A. Friedman, Y. Becker

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

The present study is concerned with the morphology and properties of the oncornavirus-like particles isolated from Raji and P3HR-1 cells that are derived from Burkitt's lymphoma. These virus particles were found to differ morphologically from mouse leukemia virus released from a human lymphoid cell line passaged in a nude mouse. The arginine-deprived cells contained neoantigens that reacted with antibodies against Rauscher mouse leukemia and simian sarcoma viruses. Thus the proteins synthesized in these cells after arginine deprivation were able to cross react with proteins from mammalian C-type particles (probably the P-30 protein).

Original languageEnglish
Pages (from-to)740-746
Number of pages7
JournalIsrael Journal of Medical Sciences
Volume13
Issue number7
StatePublished - 1977

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