Pulmonary artery pressures and outcomes after MitraClip

Yonatan Rashi, Dan Haberman*, Ivaylo Tonchev, Alona Peretz, Anna Turyan Medvedovsky, Israel Gotsman, Saar Minha, Lion Poles, Sara Shimoni, Sorel Goland, Gidon Y. Perlman, Haim D. Danenberg, Ronen Beeri, Mony Shuvy

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Aims: We evaluated the impact of MitraClip on systolic pulmonary artery pressure (sPAP) and the effects of baseline sPAP on outcomes. Methods and results: In a cohort of patients who underwent MitraClip implantation, three groups were defined according to pre-procedure sPAP levels. Clinical and echocardiographic data were compared. The study included 177 patients: 59 had severe pulmonary hypertension (PHT), 96 had mild to moderate PHT, and 22 had no PHT. In patients with pre-existing severe PHT, sPAP was reduced from 70.8 ± 9.2 to 56.8 ± 13.7 mmHg (P < 0.001), sPAP remained unchanged in patients with mild to moderate PHT but was significantly increased from 30.8 ± 4.3 to 38.6 ± 8.3 mmHg in the no-PHT group (P < 0.001). Improvement of sPAP was observed in 77% of severe PHT group, while worsening of sPAP was more common among patients with no-PHT [57% compared with 33% among the mild to moderate PHT and 7% in the severe PHT group, respectively, (P < 0.001)]. One year survival was similar among the study groups. Conclusions: MitraClip decreases PHT among patients with severe PHT. A concerning finding is that most patients with no-PHT increase their sPAP.

Original languageAmerican English
Pages (from-to)4071-4079
Number of pages9
JournalESC heart failure
Issue number6
StatePublished - Dec 2020

Bibliographical note

Publisher Copyright:
© 2020 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of the European Society of Cardiology


  • Heart failure
  • MitraClip
  • Mitral regurgitation
  • Pulmonary hypertension
  • Transcatheter mitral valve repair


Dive into the research topics of 'Pulmonary artery pressures and outcomes after MitraClip'. Together they form a unique fingerprint.

Cite this