Quaternary lidocaine derivative QX-314 activates and permeates human TRPV1 and TRPA1 to produce inhibition of sodium channels and cytotoxicity

  • Thomas Stueber*
  • , Mirjam J. Eberhardt
  • , Christoph Hadamitzky
  • , Annette Jangra
  • , Stefan Schenk
  • , Felicia Dick
  • , Carsten Stoetzer
  • , Katrin Kistner
  • , Peter W. Reeh
  • , Alexander M. Binshtok
  • , Andreas Leffler
    • *Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

43 Scopus citations

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Keyphrases

Medicine and Dentistry

Biochemistry, Genetics and Molecular Biology

Pharmacology, Toxicology and Pharmaceutical Science

Immunology and Microbiology