Rat growth hormone gene: Intervening sequences separate the mRNA regions

H. Soreq*, M. Harpold, R. Evans, J. E. Darnell, F. C. Bancroft

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Rat genomic DNA was digested with various restriction endonucleases, separated by gel electrophoresis and hybridized to 125I-labeled mRNA for the precursor protein to growth hormone. Restriction sites were found within the genomic DNA that were not found in the previously reported DNA sequence corresponding to the mRNA (19). It appears that the gene for growth hormone contains intervening sequences separating the DNA regions that specify mRNA sequences.

Original languageEnglish
Pages (from-to)2471-2482
Number of pages12
JournalNucleic Acids Research
Volume6
Issue number7
DOIs
StatePublished - 11 Jun 1979
Externally publishedYes

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