Recombinant cells produce spider silk fibers

Thomas Scheibel*, Uri Gat

*Corresponding author for this work

Research output: Contribution to specialist publicationArticle


An Israeli-German research team succeeded in using genetic engineering to produce spider web fiber in insect cell cultures spontaneously. The researchers used a baculovirus vector containing genes encoding the ADF-3 and ADF-4 proteins to transform cultured insect cells from the caterpillar of the fall armyworm. As the transformed cells began to produce the proteins, fibers formed inside the cells. Diameter of the fibers in the cells were the same as those of real spider fiber.

Original languageAmerican English
Number of pages1
Specialist publicationIndustrial Bioprocessing
StatePublished - Jan 2005


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