Reconstructing Denisovan Anatomy Using DNA Methylation Maps

David Gokhman*, Nadav Mishol, Marc de Manuel, David de Juan, Jonathan Shuqrun, Eran Meshorer, Tomas Marques-Bonet, Yoel Rak, Liran Carmel

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

42 Scopus citations

Abstract

DNA methylation maps can be used to predict anatomical features in hominins and chimpanzees, allowing for reconstruction of a putative anatomical profile of the Denisovan, currently absent from the fossil record.

Original languageAmerican English
Pages (from-to)180-192.e10
JournalCell
Volume179
Issue number1
DOIs
StatePublished - 19 Sep 2019

Bibliographical note

Publisher Copyright:
© 2019 Elsevier Inc.

Keywords

  • Denisova
  • Neanderthal
  • aDNA
  • disease
  • jaw
  • loss of function
  • methylome
  • paleoepigenetics
  • paleogenomics
  • phenotype

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