Abstract
Food intake was suppressed in rats by subcutaneous injection of hypertonic saline while intraperitoneal loading of isotonic saline increased food consumption. Hypovolemia induced by subcutaneous injection of polyethylene glycol (Carbowax, M-20), decreased food intake in rats considerably. Free access to water under food deprivation caused significant dilution of plasma while free access to food under water deprivation resulted in hypertonicity of plasma. Feeding schedules of 23 hr food and 1 hr water vs 23 hr water and 1 hr food, caused plasma osmolarity to change from 286 mOsm/kg to 318 mOsm/kg. These wide variations are discussed in relation to the interaction of plasma osmolarity with food and water intake.
| Original language | English |
|---|---|
| Pages (from-to) | 311-313 |
| Number of pages | 3 |
| Journal | Physiology and Behavior |
| Volume | 4 |
| Issue number | 3 |
| DOIs | |
| State | Published - May 1969 |
Keywords
- Drinking
- Eating
- Food deprivation
- Hypovolemia
- Plasma osmolarity
- Plasma volume
- Water deprivation