TY - JOUR
T1 - Relationships between complement activation, complement binding, and EBV absorption by human hematopoietic cell lines
AU - Yefenof, Eitan
AU - Klein, George
AU - Kvarnung, Karin
PY - 1977/6/15
Y1 - 1977/6/15
N2 - Complement consumption (C.C.) and C3 deposition on the cell membrane, visualized by membrane fluorescence (CMF), were compared in a collection of established human lymphoid lines. C.C. was independent of the presence of C3 receptors. A positive CMF reaction was seen only in lines that expressed C3 receptors, however. Trypsin treatment abolished CMF and EAC rosetting but had virtually no influence on C.C. EBV absorptive capacity correlated with both C3-receptor expression, as measured by EAC rosetting, and CMF but not with C.C. This is in line with our previous finding on the association of EBV and C3 receptors.
AB - Complement consumption (C.C.) and C3 deposition on the cell membrane, visualized by membrane fluorescence (CMF), were compared in a collection of established human lymphoid lines. C.C. was independent of the presence of C3 receptors. A positive CMF reaction was seen only in lines that expressed C3 receptors, however. Trypsin treatment abolished CMF and EAC rosetting but had virtually no influence on C.C. EBV absorptive capacity correlated with both C3-receptor expression, as measured by EAC rosetting, and CMF but not with C.C. This is in line with our previous finding on the association of EBV and C3 receptors.
UR - http://www.scopus.com/inward/record.url?scp=0017685995&partnerID=8YFLogxK
U2 - 10.1016/0008-8749(77)90024-7
DO - 10.1016/0008-8749(77)90024-7
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C2 - 194711
AN - SCOPUS:0017685995
SN - 0008-8749
VL - 31
SP - 225
EP - 233
JO - Cellular Immunology
JF - Cellular Immunology
IS - 2
ER -