Removal of tibial marrow induces increased formation of bone and cartilage in rat mandibular condyle

I. Bab*, D. Gazit, A. Massarawa, J. Sela

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

78 Scopus citations

Abstract

The present paper reports alterations in osteogenesis recorded in mandibular condyles 3-18 days after the removal of marrow tissue from tibial bones. Computerized histomorphometric evaluation of undecalcified condyles revealed a considerable increase in the thickness of condylar cartilage, in particular, the zone of provisional calcification. Measurements of the subcartilaginous trabecular bone suggested an increase in the number of osteoblasts and in their activity. The systemic enhancement of osteogenesis may be initiated by circulating factors released at the affected limb during regeneration of the marrow.

Original languageEnglish
Pages (from-to)551-555
Number of pages5
JournalCalcified Tissue International
Volume37
Issue number5
DOIs
StatePublished - Sep 1985

Keywords

  • Bone
  • Bone marrow
  • Cartilage
  • Histomorphometry
  • Mandibular condyle
  • Osteogenesis
  • Tibia

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