Resistance of companion animal parasites to antiparasitic drugs

Friederike Krämer; Gad Baneth; Filipe Dantas-Torres; Sarah Hamer; Michael R. Lappin; Domenico Otranto; Xavier Roura; Heinz Sager; Bettina Schunack; Valeria Scorza; Rebecca Traub; Timothy G. Geary

doi:10.1016/bs.apar.2025.07.002

Resistance of companion animal parasites to antiparasitic drugs

Friederike Krämer
, Gad Baneth
, Filipe Dantas-Torres
, Sarah Hamer
, Michael R. Lappin
, Domenico Otranto
, Xavier Roura
, Heinz Sager
, Bettina Schunack
, Valeria Scorza
, Rebecca Traub
, Timothy G. Geary^*

^*Corresponding author for this work

The Koret School of Veterinary Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

8 Scopus citations

Abstract

Resistance to chemotherapy continues to limit the ability to cure infectious diseases and cancer. Resistance to antiparasitic drugs is affecting control of many pathogens in human and veterinary medicine. In veterinary medicine, particular attention has been focused on resistance to parasites of livestock, including helminths, ectoparasites and protozoa, as an effect of intensive treatment regimens that promote economic sustainability of production systems. Less attention has been given to drug resistance in parasites of companion animals. We provide a comprehensive review of current knowledge of drug resistance in ectoparasites, helminths and protozoa of importance in dogs and cats to establish a baseline assessment of the field and provide recommendations for research priorities and therapeutic alternatives.

Original language	English
Title of host publication	Advances in Parasitology
Editors	Cinzia Cantacessi
Publisher	Academic Press
Pages	35-157
Number of pages	123
ISBN (Print)	9780443346378
DOIs	https://doi.org/10.1016/bs.apar.2025.07.002
State	Published - Jan 2025

Publication series

Name	Advances in Parasitology
Volume	128
ISSN (Print)	0065-308X

Bibliographical note

Publisher Copyright:
© 2025

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Acaricides
Anthelmintics
Arthropods
Canine
Cestodes
Drug resistance
Ectoparasites
Feline
Helminths
Insecticides
Nematodes
Protozoa
Trematodes

Access to Document

10.1016/bs.apar.2025.07.002

Cite this

Krämer, F., Baneth, G., Dantas-Torres, F., Hamer, S., Lappin, M. R., Otranto, D., Roura, X., Sager, H., Schunack, B., Scorza, V., Traub, R., & Geary, T. G. (2025). Resistance of companion animal parasites to antiparasitic drugs. In C. Cantacessi (Ed.), Advances in Parasitology (pp. 35-157). (Advances in Parasitology; Vol. 128). Academic Press. https://doi.org/10.1016/bs.apar.2025.07.002

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abstract = "Resistance to chemotherapy continues to limit the ability to cure infectious diseases and cancer. Resistance to antiparasitic drugs is affecting control of many pathogens in human and veterinary medicine. In veterinary medicine, particular attention has been focused on resistance to parasites of livestock, including helminths, ectoparasites and protozoa, as an effect of intensive treatment regimens that promote economic sustainability of production systems. Less attention has been given to drug resistance in parasites of companion animals. We provide a comprehensive review of current knowledge of drug resistance in ectoparasites, helminths and protozoa of importance in dogs and cats to establish a baseline assessment of the field and provide recommendations for research priorities and therapeutic alternatives.",

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AU - Hamer, Sarah

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AU - Otranto, Domenico

AU - Roura, Xavier

AU - Sager, Heinz

AU - Schunack, Bettina

AU - Scorza, Valeria

AU - Traub, Rebecca

AU - Geary, Timothy G.

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AB - Resistance to chemotherapy continues to limit the ability to cure infectious diseases and cancer. Resistance to antiparasitic drugs is affecting control of many pathogens in human and veterinary medicine. In veterinary medicine, particular attention has been focused on resistance to parasites of livestock, including helminths, ectoparasites and protozoa, as an effect of intensive treatment regimens that promote economic sustainability of production systems. Less attention has been given to drug resistance in parasites of companion animals. We provide a comprehensive review of current knowledge of drug resistance in ectoparasites, helminths and protozoa of importance in dogs and cats to establish a baseline assessment of the field and provide recommendations for research priorities and therapeutic alternatives.

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KW - Anthelmintics

KW - Arthropods

KW - Canine

KW - Cestodes

KW - Drug resistance

KW - Ectoparasites

KW - Feline

KW - Helminths

KW - Insecticides

KW - Nematodes

KW - Protozoa

KW - Trematodes

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A2 - Cantacessi, Cinzia

PB - Academic Press

ER -

Resistance of companion animal parasites to antiparasitic drugs

Abstract

Publication series

Bibliographical note

UN SDGs

Keywords

Access to Document

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