Resolving chromosome segregation in bacteria

Ronen Hazan, Ben Yehuda Sigal*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

9 Scopus citations


Bacterial chromosomes are evenly distributed between daughter cells, however no equivalent eukaryotic mitotic apparatus has been identified yet. Nevertheless, an advance in our understanding of the dynamics of the bacterial chromosome has been accomplished in recent years by adopting fluorescence microscopy techniques to visualize living bacterial cells. Here, some of the most recent studies that yield new insights into the nature of bacterial chromosome dynamics are described. In addition, we review in detail the current models that attempt to illuminate the mechanism of chromosome segregation in bacteria and discuss the possibility that a bacterial mitotic apparatus does indeed exist.

Original languageEnglish
Pages (from-to)126-139
Number of pages14
JournalJournal of Molecular Microbiology and Biotechnology
Issue number3-5
StatePublished - Sep 2006


  • Bacterial chromosome segregation
  • MreB
  • Plasmid segregation
  • RacA
  • Spo0J
  • SpoIIIE


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