Retardation of calcium oxalate precipitation by glutamic-oxalacetic-transaminase activity

R. Azoury; S. Sarig; N. Garti; S. Perlberg

doi:10.1007/BF00255939

Retardation of calcium oxalate precipitation by glutamic-oxalacetic-transaminase activity

R. Azoury^*, S. Sarig, N. Garti, S. Perlberg

^*Corresponding author for this work

Institute of Chemistry

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

It has been found that calcium oxalate stone formers have low UGOT activity compared to healthy individuals (controls). Urine from stone formers with no GOT activity and no effect on calcium oxalate precipitation was incubated with GOT for various periods. Subsequently calcium oxalate precipitation was decreased and found to be considerably retarded i.e., the pathological urine after the incubation acted in a way similar to that of normal urine. The yield of Glutamic-Oxalacetic Transaminase (GOT) activity is gultamic acid. It was shown that glutamic acid has a significant retardation effect on the precipitation of calcium oxalate stone formation. Therefore it may be suggested that GOT activity involved in glutamic acid creation in situ, has a role in kidney stone formation.

Original language	English
Pages (from-to)	169-172
Number of pages	4
Journal	Urological Research
Volume	10
Issue number	4
DOIs	https://doi.org/10.1007/BF00255939
State	Published - Oct 1982

Keywords

Calcium oxalate
Kidney Stones
L-glutamic acid
Retardation
UGOT

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10.1007/BF00255939

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title = "Retardation of calcium oxalate precipitation by glutamic-oxalacetic-transaminase activity",

abstract = "It has been found that calcium oxalate stone formers have low UGOT activity compared to healthy individuals (controls). Urine from stone formers with no GOT activity and no effect on calcium oxalate precipitation was incubated with GOT for various periods. Subsequently calcium oxalate precipitation was decreased and found to be considerably retarded i.e., the pathological urine after the incubation acted in a way similar to that of normal urine. The yield of Glutamic-Oxalacetic Transaminase (GOT) activity is gultamic acid. It was shown that glutamic acid has a significant retardation effect on the precipitation of calcium oxalate stone formation. Therefore it may be suggested that GOT activity involved in glutamic acid creation in situ, has a role in kidney stone formation.",

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AU - Azoury, R.

AU - Sarig, S.

AU - Garti, N.

AU - Perlberg, S.

PY - 1982/10

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N2 - It has been found that calcium oxalate stone formers have low UGOT activity compared to healthy individuals (controls). Urine from stone formers with no GOT activity and no effect on calcium oxalate precipitation was incubated with GOT for various periods. Subsequently calcium oxalate precipitation was decreased and found to be considerably retarded i.e., the pathological urine after the incubation acted in a way similar to that of normal urine. The yield of Glutamic-Oxalacetic Transaminase (GOT) activity is gultamic acid. It was shown that glutamic acid has a significant retardation effect on the precipitation of calcium oxalate stone formation. Therefore it may be suggested that GOT activity involved in glutamic acid creation in situ, has a role in kidney stone formation.

AB - It has been found that calcium oxalate stone formers have low UGOT activity compared to healthy individuals (controls). Urine from stone formers with no GOT activity and no effect on calcium oxalate precipitation was incubated with GOT for various periods. Subsequently calcium oxalate precipitation was decreased and found to be considerably retarded i.e., the pathological urine after the incubation acted in a way similar to that of normal urine. The yield of Glutamic-Oxalacetic Transaminase (GOT) activity is gultamic acid. It was shown that glutamic acid has a significant retardation effect on the precipitation of calcium oxalate stone formation. Therefore it may be suggested that GOT activity involved in glutamic acid creation in situ, has a role in kidney stone formation.

KW - Calcium oxalate

KW - Kidney Stones

KW - L-glutamic acid

KW - Retardation

KW - UGOT

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Retardation of calcium oxalate precipitation by glutamic-oxalacetic-transaminase activity

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