Retinal degeneration in rcs rats raised under ambient light levels

M. Kaitz; E. Auerbach

doi:10.1016/0042-6989(79)90124-X

Retinal degeneration in rcs rats raised under ambient light levels

M. Kaitz^*, E. Auerbach

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

RCS rats have an inherited, light sensitive retinal degeneration. In the present experiment, this decline was measured as a decline in ERG amplitude and is shown to be dependent on the illumination levels in the animals' living quarters. Regardless of rearing conditions the decline in ERG amplitude was nonlinear and may reflect the earlier degeneration of rods followed by the slower deterioration of the more resistant cones.

Original language	English
Pages (from-to)	79-81
Number of pages	3
Journal	Vision Research
Volume	19
Issue number	1
DOIs	https://doi.org/10.1016/0042-6989(79)90124-X
State	Published - 1979
Externally published	Yes

Keywords

RCS rats
electroretinogram
light damage
light deprivation
retinal degeneration
retinitis pigmentosa

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10.1016/0042-6989(79)90124-X

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title = "Retinal degeneration in rcs rats raised under ambient light levels",

abstract = "RCS rats have an inherited, light sensitive retinal degeneration. In the present experiment, this decline was measured as a decline in ERG amplitude and is shown to be dependent on the illumination levels in the animals' living quarters. Regardless of rearing conditions the decline in ERG amplitude was nonlinear and may reflect the earlier degeneration of rods followed by the slower deterioration of the more resistant cones.",

keywords = "RCS rats, electroretinogram, light damage, light deprivation, retinal degeneration, retinitis pigmentosa",

author = "M. Kaitz and E. Auerbach",

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AU - Auerbach, E.

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AB - RCS rats have an inherited, light sensitive retinal degeneration. In the present experiment, this decline was measured as a decline in ERG amplitude and is shown to be dependent on the illumination levels in the animals' living quarters. Regardless of rearing conditions the decline in ERG amplitude was nonlinear and may reflect the earlier degeneration of rods followed by the slower deterioration of the more resistant cones.

KW - RCS rats

KW - electroretinogram

KW - light damage

KW - light deprivation

KW - retinal degeneration

KW - retinitis pigmentosa

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Retinal degeneration in rcs rats raised under ambient light levels

Abstract

Keywords

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