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Revascularization of chronic total occlusions: Time to reconsider?

  • Bradley H. Strauss*
  • , Mony Shuvy
  • , Harindra C. Wijeysundera
  • *Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

51 Scopus citations

Abstract

Up to 20% of all coronary angiograms reveal coronary chronic total occlusions (CTOs). The lack of robust type A evidence with hard clinical outcomes on the benefits of CTO revascularization has hampered attempts to develop recommendations regarding the optimal management of CTOs. This review presents issues surrounding CTO revascularization within the framework of the appropriate use criteria ratings. Appropriate use criteria ratings downgrade CTO percutaneous coronary intervention revascularization relative to non-CTOs and to surgical revascularization. Specific aspects of CTO revascularization include ischemic burden, impact of revascularization on quality of life, risks in CTO revascularization, and the importance of complete revascularization. Contemporary data suggest CTO revascularization may have substantial impact on patient outcomes; thus, revascularization should likely be held to similar criteria as nonocclusive lesions. However, additional large clinical trial data are required to more definitively determine CTO revascularization guidelines.

Original languageEnglish
Pages (from-to)1281-1289
Number of pages9
JournalJournal of the American College of Cardiology
Volume64
Issue number12
DOIs
StatePublished - 23 Sep 2014
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2014 American College of Cardiology Foundation.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • bypass surgery
  • chronic total occlusions
  • coronary artery disease
  • revascularization

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