Reversible Ag+-crosslinked DNA hydrogels

Weiwei Guo; Xiu Juan Qi; Ron Orbach; Chun Hua Lu; Lina Freage; Iris Mironi-Harpaz; Dror Seliktar; Huang Hao Yang; Itamar Willner

doi:10.1039/c3cc49140d

Reversible Ag⁺-crosslinked DNA hydrogels

Weiwei Guo
, Xiu Juan Qi
, Ron Orbach
, Chun Hua Lu
, Lina Freage
, Iris Mironi-Harpaz
, Dror Seliktar
, Huang Hao Yang
, Itamar Willner^*

^*Corresponding author for this work

Institute of Chemistry

Research output: Contribution to journal › Article › peer-review

140 Scopus citations

Abstract

DNA hydrogels, consisting of Y-shaped nucleic acid subunits or of nucleic acid-functionalized acrylamide chains, undergo switchable gel-to-solution transitions. The Ag⁺-stimulated formation of cytosine–Ag⁺–cytosine complexes results in the crosslinking of the units to yield the hydrogels, while the cysteamine-induced elimination of the Ag⁺ ions dissociates the hydrogels into a solution phase.

Original language	English
Pages (from-to)	4065-4068
Number of pages	4
Journal	Chemical Communications
Volume	50
Issue number	31
DOIs	https://doi.org/10.1039/c3cc49140d
State	Published - 20 Mar 2014

Access to Document

10.1039/c3cc49140d

Cite this

@article{7740696373b1432f9bb9b1b794da0bba,

title = "Reversible Ag+-crosslinked DNA hydrogels",

abstract = "DNA hydrogels, consisting of Y-shaped nucleic acid subunits or of nucleic acid-functionalized acrylamide chains, undergo switchable gel-to-solution transitions. The Ag+-stimulated formation of cytosine–Ag+–cytosine complexes results in the crosslinking of the units to yield the hydrogels, while the cysteamine-induced elimination of the Ag+ ions dissociates the hydrogels into a solution phase.",

author = "Weiwei Guo and Qi, \{Xiu Juan\} and Ron Orbach and Lu, \{Chun Hua\} and Lina Freage and Iris Mironi-Harpaz and Dror Seliktar and Yang, \{Huang Hao\} and Itamar Willner",

year = "2014",

month = mar,

day = "20",

doi = "10.1039/c3cc49140d",

language = "אנגלית",

volume = "50",

pages = "4065--4068",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "31",

}

TY - JOUR

T1 - Reversible Ag+-crosslinked DNA hydrogels

AU - Guo, Weiwei

AU - Qi, Xiu Juan

AU - Orbach, Ron

AU - Lu, Chun Hua

AU - Freage, Lina

AU - Mironi-Harpaz, Iris

AU - Seliktar, Dror

AU - Yang, Huang Hao

AU - Willner, Itamar

PY - 2014/3/20

Y1 - 2014/3/20

N2 - DNA hydrogels, consisting of Y-shaped nucleic acid subunits or of nucleic acid-functionalized acrylamide chains, undergo switchable gel-to-solution transitions. The Ag+-stimulated formation of cytosine–Ag+–cytosine complexes results in the crosslinking of the units to yield the hydrogels, while the cysteamine-induced elimination of the Ag+ ions dissociates the hydrogels into a solution phase.

AB - DNA hydrogels, consisting of Y-shaped nucleic acid subunits or of nucleic acid-functionalized acrylamide chains, undergo switchable gel-to-solution transitions. The Ag+-stimulated formation of cytosine–Ag+–cytosine complexes results in the crosslinking of the units to yield the hydrogels, while the cysteamine-induced elimination of the Ag+ ions dissociates the hydrogels into a solution phase.

UR - https://www.scopus.com/pages/publications/84897831046

U2 - 10.1039/c3cc49140d

DO - 10.1039/c3cc49140d

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

C2 - 24616906

AN - SCOPUS:84897831046

SN - 1359-7345

VL - 50

SP - 4065

EP - 4068

JO - Chemical Communications

JF - Chemical Communications

IS - 31

ER -

Reversible Ag⁺-crosslinked DNA hydrogels

Abstract

Access to Document

Other files and links

Fingerprint

Cite this