Reversible cross-linking of cellular components of adherent fibroblasts to fibronectin and lectin-coated substrata

J. D. Aplin; R. C. Hughes; C. L. Jaffe; N. Sharon

doi:10.1016/0014-4827(81)90453-5

Reversible cross-linking of cellular components of adherent fibroblasts to fibronectin and lectin-coated substrata

J. D. Aplin, R. C. Hughes^*, C. L. Jaffe, N. Sharon

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

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Abstract

Using matrix-immobilized proteins containing photo-labile cross-linking reagents we have been able to probe the underside of cells in the early stages of active spreading. Similar cellular components of hamster fibroblasts appear to be present in closest proximity to substrata containing fibronectin, ricin, concanavalin A (conA) or soybean agglutinin (SBA).

Original language	English
Pages (from-to)	488-494
Number of pages	7
Journal	Experimental Cell Research
Volume	134
Issue number	2
DOIs	https://doi.org/10.1016/0014-4827(81)90453-5
State	Published - Aug 1981
Externally published	Yes

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10.1016/0014-4827(81)90453-5

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abstract = "Using matrix-immobilized proteins containing photo-labile cross-linking reagents we have been able to probe the underside of cells in the early stages of active spreading. Similar cellular components of hamster fibroblasts appear to be present in closest proximity to substrata containing fibronectin, ricin, concanavalin A (conA) or soybean agglutinin (SBA).",

author = "Aplin, {J. D.} and Hughes, {R. C.} and Jaffe, {C. L.} and N. Sharon",

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AB - Using matrix-immobilized proteins containing photo-labile cross-linking reagents we have been able to probe the underside of cells in the early stages of active spreading. Similar cellular components of hamster fibroblasts appear to be present in closest proximity to substrata containing fibronectin, ricin, concanavalin A (conA) or soybean agglutinin (SBA).

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Reversible cross-linking of cellular components of adherent fibroblasts to fibronectin and lectin-coated substrata

Abstract

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