Ribonuclease recruitment using a small molecule reduced c9ALS/FTD r(G4C2) repeat expansion in vitro and in vivo ALS models

Jessica A. Bush, Haruo Aikawa, Rita Fuerst, Yue Li, Andrei Ursu, Samantha M. Meyer, Raphael I. Benhamou, Jonathan L. Chen, Tanya Khan, Sarah Wagner-Griffin, Montina J. van Meter, Yuquan Tong, Hailey Olafson, Kendra K. McKee, Jessica L. Childs-Disney, Tania F. Gendron, Yongjie Zhang, Alyssa N. Coyne, Eric T. Wang, Ilyas YildirimKye Won Wang, Leonard Petrucelli, Jeffrey D. Rothstein, Matthew D. Disney*

*Corresponding author for this work

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Neuroscience

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Biochemistry, Genetics and Molecular Biology