Role of Interferon in the Pathogenesis of Inflammatory Bowel Disease

D. Rachmilewitz; R. Stalnikowicz; F. Karmeli; A. Panet; C. Fiocchi

doi:10.1007/978-94-009-4269-1_8

Role of Interferon in the Pathogenesis of Inflammatory Bowel Disease

D. Rachmilewitz
, R. Stalnikowicz
, F. Karmeli
, A. Panet
, C. Fiocchi

Institute for Medical Research Israel-Canada (IMRIC)

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

The etiology of ulcerative colitis and Crohn’s disease is still unknown. Circulating immune interferon has been detected in patients with inflammatory bowel disease IBD (1, 2). Interferon, besides its antiviral properties, is also an immune modulator which can induce or perpetuate some of the immunological abnormalities in IBD: decrease the number of supressor T cells, induction of hypergammaglobulinemia and enhancement of the defective natural killing activity reported in these patients (3, 4, 5).

Original language	American English
Title of host publication	Inflammatory Bowel Diseases 1986: Proceedings of the Second International Symposium on Inflamatory Bowel Diseases, Jerusalem, September 8–11, 1985
Editors	Daniel Rachmilewitz
Place of Publication	Dordrecht
Publisher	Springer Netherlands
Pages	87-94
Number of pages	8
ISBN (Print)	978-94-009-4269-1
DOIs	https://doi.org/10.1007/978-94-009-4269-1_8
State	Published - 1986

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10.1007/978-94-009-4269-1_8

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Rachmilewitz, D., Stalnikowicz, R., Karmeli, F., Panet, A., & Fiocchi, C. (1986). Role of Interferon in the Pathogenesis of Inflammatory Bowel Disease. In D. Rachmilewitz (Ed.), Inflammatory Bowel Diseases 1986: Proceedings of the Second International Symposium on Inflamatory Bowel Diseases, Jerusalem, September 8–11, 1985 (pp. 87-94). Springer Netherlands. https://doi.org/10.1007/978-94-009-4269-1_8

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abstract = "The etiology of ulcerative colitis and Crohn{\textquoteright}s disease is still unknown. Circulating immune interferon has been detected in patients with inflammatory bowel disease IBD (1, 2). Interferon, besides its antiviral properties, is also an immune modulator which can induce or perpetuate some of the immunological abnormalities in IBD: decrease the number of supressor T cells, induction of hypergammaglobulinemia and enhancement of the defective natural killing activity reported in these patients (3, 4, 5).",

author = "D. Rachmilewitz and R. Stalnikowicz and F. Karmeli and A. Panet and C. Fiocchi",

year = "1986",

doi = "10.1007/978-94-009-4269-1\_8",

language = "American English",

isbn = "978-94-009-4269-1",

pages = "87--94",

editor = "Daniel Rachmilewitz",

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publisher = "Springer Netherlands",

address = "Netherlands",

}

Rachmilewitz, D, Stalnikowicz, R, Karmeli, F, Panet, A & Fiocchi, C 1986, Role of Interferon in the Pathogenesis of Inflammatory Bowel Disease. in D Rachmilewitz (ed.), Inflammatory Bowel Diseases 1986: Proceedings of the Second International Symposium on Inflamatory Bowel Diseases, Jerusalem, September 8–11, 1985. Springer Netherlands, Dordrecht, pp. 87-94. https://doi.org/10.1007/978-94-009-4269-1_8

Role of Interferon in the Pathogenesis of Inflammatory Bowel Disease. / Rachmilewitz, D.; Stalnikowicz, R.; Karmeli, F. et al.
Inflammatory Bowel Diseases 1986: Proceedings of the Second International Symposium on Inflamatory Bowel Diseases, Jerusalem, September 8–11, 1985. ed. / Daniel Rachmilewitz. Dordrecht: Springer Netherlands, 1986. p. 87-94.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

TY - CHAP

T1 - Role of Interferon in the Pathogenesis of Inflammatory Bowel Disease

AU - Rachmilewitz, D.

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AU - Karmeli, F.

AU - Panet, A.

AU - Fiocchi, C.

PY - 1986

Y1 - 1986

N2 - The etiology of ulcerative colitis and Crohn’s disease is still unknown. Circulating immune interferon has been detected in patients with inflammatory bowel disease IBD (1, 2). Interferon, besides its antiviral properties, is also an immune modulator which can induce or perpetuate some of the immunological abnormalities in IBD: decrease the number of supressor T cells, induction of hypergammaglobulinemia and enhancement of the defective natural killing activity reported in these patients (3, 4, 5).

AB - The etiology of ulcerative colitis and Crohn’s disease is still unknown. Circulating immune interferon has been detected in patients with inflammatory bowel disease IBD (1, 2). Interferon, besides its antiviral properties, is also an immune modulator which can induce or perpetuate some of the immunological abnormalities in IBD: decrease the number of supressor T cells, induction of hypergammaglobulinemia and enhancement of the defective natural killing activity reported in these patients (3, 4, 5).

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SP - 87

EP - 94

BT - Inflammatory Bowel Diseases 1986: Proceedings of the Second International Symposium on Inflamatory Bowel Diseases, Jerusalem, September 8–11, 1985

A2 - Rachmilewitz, Daniel

PB - Springer Netherlands

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ER -

Rachmilewitz D, Stalnikowicz R, Karmeli F, Panet A, Fiocchi C. Role of Interferon in the Pathogenesis of Inflammatory Bowel Disease. In Rachmilewitz D, editor, Inflammatory Bowel Diseases 1986: Proceedings of the Second International Symposium on Inflamatory Bowel Diseases, Jerusalem, September 8–11, 1985. Dordrecht: Springer Netherlands. 1986. p. 87-94 doi: 10.1007/978-94-009-4269-1_8

Role of Interferon in the Pathogenesis of Inflammatory Bowel Disease

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