Role of metal complexes in the formation-detoxication action of active oxygen species

Gidon Czapski*, Sara Goldstein

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

A general mechanism for the action of metal compounds either in enhancing the biological damage induced by active oxygen species or in protecting the biological target against these species is proposed. The effect of several copper complexes and iron and copper bleomycin complexes on DNA cleavage is discussed in view of this mechanism.

Original languageEnglish
Pages (from-to)21-28
Number of pages8
JournalBioelectrochemistry and Bioenergetics
Volume18
Issue number1-3
DOIs
StatePublished - Dec 1987

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