Abstract
The use of absorption enhancers to increase drug bioavailability after oral administration was demonstrated. Sodium decanoate was employed for the enhancement of drug absorption following rectal administration. The non-synchronous formulations were significantly inferior to the synchronous ones in terms of the absorption enhancement of sulpiride. The extent and duration of the enhancement SD effect could be fine-tuned by manipulating the amounts of Hydroxypropyl methylcellulose in the synchronous oral formulations.
| Original language | English |
|---|---|
| Pages (from-to) | 263-264 |
| Number of pages | 2 |
| Journal | American Chemical Society, Polymer Preprints, Division of Polymer Chemistry |
| Volume | 40 |
| Issue number | 1 |
| State | Published - Mar 1999 |
| Event | Proceedings of the 1999 ACS Anaheim Meeting - Anaheim, CA, USA Duration: 21 Mar 1999 → 25 Mar 1999 |
Fingerprint
Dive into the research topics of 'Role of synchronous release of sodium decanoate on sulpiride absorption in the intestine of the rat'. Together they form a unique fingerprint.Cite this
- APA
- Author
- BIBTEX
- Harvard
- Standard
- RIS
- Vancouver