Role of the endocannabinoid system in hepatic lipogenesis

Joseph Tam

doi:10.1007/978-3-319-25065-6_6

Role of the endocannabinoid system in hepatic lipogenesis

Joseph Tam^*

^*Corresponding author for this work

School of Pharmacy

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

2 Scopus citations

Abstract

Endocannabinoids are endogenous lipid mediators recognized by the cannabinoid-1 and 2 (CB₁ and CB₂, respectively) receptors that mediate the effects of marijuana. The endocannabinoid system, consisting of endocannabinoids (eCBs), their receptors, and the enzymes involved in their biosynthesis and degradation, is present in many tissues including the liver. The present chapter reviews accumulating evidence that the eCB system is involved in the regulation of de novo hepatic lipogenesis.

Original language	English
Title of host publication	Hepatic De Novo Lipogenesis and Regulation of Metabolism
Publisher	Springer International Publishing
Pages	131-142
Number of pages	12
ISBN (Electronic)	9783319250656
ISBN (Print)	9783319250632
DOIs	https://doi.org/10.1007/978-3-319-25065-6_6
State	Published - 1 Jan 2015

Bibliographical note

Publisher Copyright:
© Springer International Publishing Switzerland 2016.

Keywords

CB receptor
CB receptor
Diet-induced obesity
Endocannabinoids
Fatty liver
Hepatic lipogenesis
Monounsaturated fatty acids

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/978-3-319-25065-6_6

Cite this

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Role of the endocannabinoid system in hepatic lipogenesis

Abstract

Bibliographical note

Keywords

UN SDGs

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