Role of the endocannabinoid system in hepatic lipogenesis

Joseph Tam*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

2 Scopus citations


Endocannabinoids are endogenous lipid mediators recognized by the cannabinoid-1 and 2 (CB1 and CB2, respectively) receptors that mediate the effects of marijuana. The endocannabinoid system, consisting of endocannabinoids (eCBs), their receptors, and the enzymes involved in their biosynthesis and degradation, is present in many tissues including the liver. The present chapter reviews accumulating evidence that the eCB system is involved in the regulation of de novo hepatic lipogenesis.

Original languageAmerican English
Title of host publicationHepatic De Novo Lipogenesis and Regulation of Metabolism
PublisherSpringer International Publishing
Number of pages12
ISBN (Electronic)9783319250656
ISBN (Print)9783319250632
StatePublished - 1 Jan 2015

Bibliographical note

Publisher Copyright:
© Springer International Publishing Switzerland 2016.


  • CB receptor
  • CB receptor
  • Diet-induced obesity
  • Endocannabinoids
  • Fatty liver
  • Hepatic lipogenesis
  • Monounsaturated fatty acids


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