Rosuvastatin restores liver tissue-resident NK cell activation in aged mice by improving mitochondrial function

Keyphrases

• Tissue-resident Natural Killer Cells 100%
• Mitochondrial Function 100%
• Liver Tissue 100%
• Natural Killer Cell Activity 100%
• Aged Mice 100%
• Rosuvastatin 100%
• TrnK 100%
• Liver 60%
• Aging 40%
• Senescence 40%
• Natural Killer Cells 40%
• Mitochondrial Biogenesis 40%
• Cholesterol Accumulation 40%
• Metabolic Biomarkers 40%
• Functional Candidate Gene 40%
• Apoptosis 20%
• Interleukin-1β 20%
• Inflammatory Cytokines 20%
• Receptor Expression 20%
• Chemoattractant 20%
• Quantitative PCR 20%
• Flow Cytometry 20%
• Tumor 20%
• Cholesterol 20%
• C57BL 20%
• Cell Count 20%
• Interleukin-6 20%
• NKp46 20%
• Interleukin-2 20%
• Age-related 20%
• Liver Injury 20%
• Synthetase 20%
• Functional Impairment 20%
• Chemotaxis 20%
• Gradual Increase 20%
• Aging Effect 20%
• Mitochondrial Markers 20%
• CXCL8 20%
• Cell Activation 20%
• Chemokine Receptor CCR2 20%
• CXCR1 20%
• HMG-CoA Reductase 20%
• Histological Markers 20%
• TIGIT 20%
• Cell Functionality 20%
• Cholesterol Metabolism 20%
• Senescence Markers 20%
• Serum Markers 20%
• Seahorse 20%
• Peroxisome Proliferator-activated Receptor-γ coactivator-1α (PGC-1α) 20%
• Mevalonate Kinase 20%
• HSPA9 20%
• Chemokine Ligand 2 (CCL2) 20%
• Programmed Cell Death Protein 1 (PD-1) 20%
• CD107a 20%
• Linear Increase 20%
• Chemoattractant Receptors 20%
• Liver Injury Markers 20%
• HMG-CoA 20%

Biochemistry, Genetics and Molecular Biology

• Natural Killer Cell 100%
• Cell Activation 100%
• Rosuvastatin 100%
• Cholesterol 60%
• Marker Gene 40%
• Mitochondrial Biogenesis 40%
• Cell Count 20%
• Interleukin-1 20%
• Interleukin 6 20%
• Interleukin 2 20%
• P21 20%
• P16 20%
• Chemotaxis 20%
• Proinflammatory Cytokine 20%
• HMG-CoA 20%
• Chemokine Receptor 20%
• HMG-CoA Reductase 20%
• TFAM 20%
• CCL2 20%
• Cholesterol Metabolism 20%
• TIGIT 20%
• Seahorse 20%
• Flow Cytometry 20%
• Reverse Transcription Polymerase Chain Reaction 20%
• Programmed Cell Death 20%
• Mevalonate Kinase 20%
• CCR2 20%
• LAG3 20%

Immunology and Microbiology

• Natural Killer Cell 100%
• Liver Tissue 100%
• Cell Activation 100%
• Chemoattractant 40%
• Marker Gene 40%
• Mitochondrial Biogenesis 40%
• Interleukin 1 20%
• Infectious Disease 20%
• Proinflammatory Cytokine 20%
• Interleukin 6 20%
• Cell Count 20%
• Interleukin 2 20%
• Chemotaxis 20%
• Natural Cytotoxicity Triggering Receptor 1 20%
• Chemokine Receptor CCR2 20%
• CCL2 20%
• Cholesterol Metabolism 20%
• Seahorse 20%
• Reverse Transcription Polymerase Chain Reaction 20%
• Programmed Cell Death 20%
• Infection 20%
• Kinase 20%
• Phosphotransferase 20%
• LAG3 20%