TY - JOUR
T1 - Saccharin preferences in prepubertal male and female rats
T2 - Relationship to self-stimulation
AU - Cohen, Edna
AU - Lieblich, Israel
AU - Ganchrow, Judith R.
PY - 1982/9
Y1 - 1982/9
N2 - Saccharin preferences were studied in 48 male and female prepubertal rats (22-23 days old at the beginning of the experiment) of four genetic lines (LC1-low, LC1-high, LC2-low, and LC2-high) which differed in their inherent tendencies to self-stimulate. Sodium saccharin solutions of 0.1, 0.3, 0.5, 1, 3, 10, and 30 mM concentrations were used against water in two-bottle tests. It was found that (a) prepubertal rats prefer saccharin solutions to water, with the range of favored concentrations similar to that of adults; (b) male and female prepubertal rats do not differ as to saccharin preferences; (c) within the LC2 population, animals of the genetically high self-stimulating line prefer saccharin more than do their LC2-low counterparts; no such differentiation of the LC1 high and low lines was observed.
AB - Saccharin preferences were studied in 48 male and female prepubertal rats (22-23 days old at the beginning of the experiment) of four genetic lines (LC1-low, LC1-high, LC2-low, and LC2-high) which differed in their inherent tendencies to self-stimulate. Sodium saccharin solutions of 0.1, 0.3, 0.5, 1, 3, 10, and 30 mM concentrations were used against water in two-bottle tests. It was found that (a) prepubertal rats prefer saccharin solutions to water, with the range of favored concentrations similar to that of adults; (b) male and female prepubertal rats do not differ as to saccharin preferences; (c) within the LC2 population, animals of the genetically high self-stimulating line prefer saccharin more than do their LC2-low counterparts; no such differentiation of the LC1 high and low lines was observed.
UR - http://www.scopus.com/inward/record.url?scp=0020306252&partnerID=8YFLogxK
U2 - 10.1016/S0163-1047(82)90278-3
DO - 10.1016/S0163-1047(82)90278-3
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C2 - 7168733
AN - SCOPUS:0020306252
SN - 0163-1047
VL - 36
SP - 88
EP - 93
JO - Behavioral and Neural Biology
JF - Behavioral and Neural Biology
IS - 1
ER -