Safety and Effectiveness of QingDai (Indigo naturalis) in Children With Mild-to-Moderate Ulcerative Colitis: A Short-Term 6-Week Open-Label Trial

Dotan Yogev; Yael Weintraub; Oren Ledder; Manar Matar; Alex Krauthammer; Zivia Shavit-Brunschwig; Amichay Rotstein; Max E. Godfrey; Amit Assa; Raanan Shamir; Dan Turner; Nir Salomon; Esther Orlanski-Meyer; Dror S. Shouval

doi:10.1093/ibd/izaf119

Safety and Effectiveness of QingDai (Indigo naturalis) in Children With Mild-to-Moderate Ulcerative Colitis: A Short-Term 6-Week Open-Label Trial

Dotan Yogev
, Yael Weintraub
, Oren Ledder
, Manar Matar
, Alex Krauthammer
, Zivia Shavit-Brunschwig
, Amichay Rotstein
, Max E. Godfrey
, Amit Assa
, Raanan Shamir
, Dan Turner
, Nir Salomon
, Esther Orlanski-Meyer
, Dror S. Shouval^*

^*Corresponding author for this work

Institute for Medical Research Israel-Canada (IMRIC)

Research output: Contribution to journal › Article › peer-review

Abstract

A 6-week course of QingDai (Indigo naturlis) was safe and effective in inducing remission in an open-label study of pediatric patients with mild–moderate ulcerative colitis.

Original language	English
Pages (from-to)	2917-2920
Number of pages	4
Journal	Inflammatory Bowel Diseases
Volume	31
Issue number	10
DOIs	https://doi.org/10.1093/ibd/izaf119
State	Published - 1 Oct 2025

Bibliographical note

Publisher Copyright:
© The Author(s) 2025. Published by Oxford University Press on behalf of Crohn’s & Colitis Foundation. All rights reserved.

Keywords

Chinese medicine
colitis
complimentary medicine
herbal
treatment

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10.1093/ibd/izaf119

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Yogev, D., Weintraub, Y., Ledder, O., Matar, M., Krauthammer, A., Shavit-Brunschwig, Z., Rotstein, A., Godfrey, M. E., Assa, A., Shamir, R., Turner, D., Salomon, N., Orlanski-Meyer, E., & Shouval, D. S. (2025). Safety and Effectiveness of QingDai (Indigo naturalis) in Children With Mild-to-Moderate Ulcerative Colitis: A Short-Term 6-Week Open-Label Trial. Inflammatory Bowel Diseases, 31(10), 2917-2920. https://doi.org/10.1093/ibd/izaf119

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abstract = "A 6-week course of QingDai (Indigo naturlis) was safe and effective in inducing remission in an open-label study of pediatric patients with mild–moderate ulcerative colitis.",

keywords = "Chinese medicine, colitis, complimentary medicine, herbal, treatment",

author = "Dotan Yogev and Yael Weintraub and Oren Ledder and Manar Matar and Alex Krauthammer and Zivia Shavit-Brunschwig and Amichay Rotstein and Godfrey, \{Max E.\} and Amit Assa and Raanan Shamir and Dan Turner and Nir Salomon and Esther Orlanski-Meyer and Shouval, \{Dror S.\}",

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Yogev, D, Weintraub, Y, Ledder, O, Matar, M, Krauthammer, A, Shavit-Brunschwig, Z, Rotstein, A, Godfrey, ME, Assa, A, Shamir, R, Turner, D, Salomon, N, Orlanski-Meyer, E & Shouval, DS 2025, 'Safety and Effectiveness of QingDai (Indigo naturalis) in Children With Mild-to-Moderate Ulcerative Colitis: A Short-Term 6-Week Open-Label Trial', Inflammatory Bowel Diseases, vol. 31, no. 10, pp. 2917-2920. https://doi.org/10.1093/ibd/izaf119

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AU - Ledder, Oren

AU - Matar, Manar

AU - Krauthammer, Alex

AU - Shavit-Brunschwig, Zivia

AU - Rotstein, Amichay

AU - Godfrey, Max E.

AU - Assa, Amit

AU - Shamir, Raanan

AU - Turner, Dan

AU - Salomon, Nir

AU - Orlanski-Meyer, Esther

AU - Shouval, Dror S.

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AB - A 6-week course of QingDai (Indigo naturlis) was safe and effective in inducing remission in an open-label study of pediatric patients with mild–moderate ulcerative colitis.

KW - Chinese medicine

KW - colitis

KW - complimentary medicine

KW - herbal

KW - treatment

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ER -

Safety and Effectiveness of QingDai (Indigo naturalis) in Children With Mild-to-Moderate Ulcerative Colitis: A Short-Term 6-Week Open-Label Trial

Abstract

Bibliographical note

Keywords

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