Scanning tunneling spectroscopy of single DNA molecules

Dmitry A. Ryndyk, Errez Shapir, Danny Porath*, Arrigo Calzolari, Rosa Di Felice, Gianaurelio Cuniberti

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


We briefly present the results of recent experiments of transverse scanning tunneling spectroscopy of homogeneous poly(dG)-poly(dC) DNA molecules and discuss them in the light of theoretical investigation. A semiempirical theoretical model is adopted to describe the transverse tunneling current across a DNA molecule placed between a metallic gold substrate and a metallic STM tip. We show that the main trends in the positions and relative magnitudes of the conductance peaks can be explained by a minimal model of a double tunnel junction with the molecule-electrode couplings and the applied voltage explicitly taken into account.

Original languageAmerican English
Pages (from-to)1651-1656
Number of pages6
JournalACS Nano
Issue number7
StatePublished - 28 Jul 2009


  • DNA
  • Molecular nanoelectronics
  • Scanning probe microscopy
  • Theoretical modeling


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