TY - JOUR
T1 - Seasonal Fluctuations in Acute Upper Gastrointestinal Bleeding
T2 - Lack of Effect of Nonsteroidal Anti‐inflammatory Drugs
AU - Zimmerman, J.
AU - Arnon, R.
AU - Beeri, R.
AU - Keret, D.
AU - Lysy, J.
AU - Ligumski, M.
AU - Gonzalez, J.
AU - Fich, A.
AU - Ackerman, Z.
AU - Goldin, E.
PY - 1992/11
Y1 - 1992/11
N2 - The seasonal pattern of community‐based acute bleeding from the upper gastrointestinal (UGI) tract was studied prospectively in 1988‐1991. Out of 3343 emergency admissions to the Departments of General Surgery, 321 (9.6%) were due to acute UGI bleeding. There was a significant monthly variation in the total number of admissions, as well as in the number of admissions due to acute UGI bleeding (p < 0.0001). However, there was no correlation between the two. Significant seasonal fluctuations were noted both in the absolute number of admissions due to acute UGI bleeding and in the percentage of UGI bleeding admissions of the total number of admissions to the Departments of General Surgery (p= 0.0002). During summer (July through September), the incidence declined significantly to a nadir of 5.5% of total number of admissions in July. The seasonal fluctuation correlated closely with the incidence of duodenal ulcer, but not with that of gastric ulcer. The seasonal pattern was consistent both in patients who had used aspirin or other nonsteroidal anti‐inflammatory drugs as well as in those who had not.
AB - The seasonal pattern of community‐based acute bleeding from the upper gastrointestinal (UGI) tract was studied prospectively in 1988‐1991. Out of 3343 emergency admissions to the Departments of General Surgery, 321 (9.6%) were due to acute UGI bleeding. There was a significant monthly variation in the total number of admissions, as well as in the number of admissions due to acute UGI bleeding (p < 0.0001). However, there was no correlation between the two. Significant seasonal fluctuations were noted both in the absolute number of admissions due to acute UGI bleeding and in the percentage of UGI bleeding admissions of the total number of admissions to the Departments of General Surgery (p= 0.0002). During summer (July through September), the incidence declined significantly to a nadir of 5.5% of total number of admissions in July. The seasonal fluctuation correlated closely with the incidence of duodenal ulcer, but not with that of gastric ulcer. The seasonal pattern was consistent both in patients who had used aspirin or other nonsteroidal anti‐inflammatory drugs as well as in those who had not.
UR - http://www.scopus.com/inward/record.url?scp=0026438778&partnerID=8YFLogxK
U2 - 10.1111/j.1572-0241.1992.tb02739.x
DO - 10.1111/j.1572-0241.1992.tb02739.x
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C2 - 1442678
AN - SCOPUS:0026438778
SN - 0002-9270
VL - 87
SP - 1587
EP - 1590
JO - American Journal of Gastroenterology
JF - American Journal of Gastroenterology
IS - 11
ER -