Seasonal variation in sensitivity of guinea pig tissues to agonists

Marta Weinstock; Sandra Shoham

doi:10.1038/251427a0

Seasonal variation in sensitivity of guinea pig tissues to agonists

Marta Weinstock^*, Sandra Shoham

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

WE have observed a marked and consistent seasonal variation in the sensitivity of guinea pig tissue to acetylcholine (ACh). Ilea taken from guinea pigs during the summer months (May to September) were much less sensitive to the stimulant effect of ACh than those removed during the winter (November to February). Dawson, Hemsworth and Stockham¹ also noted that the response of the ileum to spasmogens varied widely at different times of the year, but they gave no specific details.

Original language	English
Pages (from-to)	427-428
Number of pages	2
Journal	Nature
Volume	251
Issue number	5474
DOIs	https://doi.org/10.1038/251427a0
State	Published - 1974
Externally published	Yes

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title = "Seasonal variation in sensitivity of guinea pig tissues to agonists",

abstract = "WE have observed a marked and consistent seasonal variation in the sensitivity of guinea pig tissue to acetylcholine (ACh). Ilea taken from guinea pigs during the summer months (May to September) were much less sensitive to the stimulant effect of ACh than those removed during the winter (November to February). Dawson, Hemsworth and Stockham1 also noted that the response of the ileum to spasmogens varied widely at different times of the year, but they gave no specific details.",

author = "Marta Weinstock and Sandra Shoham",

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AU - Shoham, Sandra

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AB - WE have observed a marked and consistent seasonal variation in the sensitivity of guinea pig tissue to acetylcholine (ACh). Ilea taken from guinea pigs during the summer months (May to September) were much less sensitive to the stimulant effect of ACh than those removed during the winter (November to February). Dawson, Hemsworth and Stockham1 also noted that the response of the ileum to spasmogens varied widely at different times of the year, but they gave no specific details.

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Seasonal variation in sensitivity of guinea pig tissues to agonists

Abstract

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