Abstract
Insect toxin (IT), a highly lethal and paralytic protein purified from scorpion venom, has been used in binding experiments with different tissue preparations of Locusta migratoria. A clear, specific binding of a high affinity was obtained only between the radio-iodinated toxin and the nervous tissue extracts. Assays with a similar nervous tissue preparation derived from a crustacean (crayfish) resulted in a low and non-specific binding of the toxin. The present data support the notion of a selective action of IT on insect nervous tissue and may indicate a certain structural uniqueness in this system.
Original language | English |
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Pages (from-to) | 343-346 |
Number of pages | 4 |
Journal | Insect Biochemistry |
Volume | 9 |
Issue number | 4 |
DOIs | |
State | Published - 1979 |
Keywords
- insect toxin
- Locusta
- nervous tissue
- radio-iodination
- scorpion venom
- selective action
- specific binding